Intracavitary (pleural, peritoneal) chemotherapy may involve which of the following?

Intracavitary (pleural, peritoneal) chemotherapy may involve which of the following?

• A. Radio isotopes
• B. Bleomycin
• C. Temozolomide
• D. Capecitabine

Answer: (A)

Intracavitary therapy within a pleural or peritoneal space can use specialized agents that stay inside the cavity and act locally. This realm includes radiopharmaceuticals, where a radioisotope is delivered into the cavity to emit radiation directly to tumor cells lining the cavity surfaces. The key idea is delivering targeted radiation within the space to control tumor burden and malignant effusions with limited systemic exposure. The other drugs listed are traditional cytotoxic chemotherapy agents; they can be used intraperitoneally in some regimens, but they are not radioactive. So the modality that specifically fits intracavitary radiopharmaceutical approaches is the use of radioisotopes.

Intracavitary therapy within a pleural or peritoneal space can use specialized agents that stay inside the cavity and act locally. This realm includes radiopharmaceuticals, where a radioisotope is delivered into the cavity to emit radiation directly to tumor cells lining the cavity surfaces. The key idea is delivering targeted radiation within the space to control tumor burden and malignant effusions with limited systemic exposure. The other drugs listed are traditional cytotoxic chemotherapy agents; they can be used intraperitoneally in some regimens, but they are not radioactive. So the modality that specifically fits intracavitary radiopharmaceutical approaches is the use of radioisotopes.